Over-Nite Sensation is the twelfth album by The Mothers of Invention (credited as The Mothers), and the seventeenth album overall by Frank Zappa, released in September 1973. It was Zappa's first album released on his DiscReet label.

Frank Zappa wanted to use backup singers on the songs "I'm the Slime", "Dirty Love", "Zomby Woof", "Dinah-Moe Humm" and "Montana". His road manager suggested The Ikettes, and Ike & Tina Turner were contacted. Ike Turner insisted that Zappa pay the singers, including Tina Turner, no more than $25 per song. However, an invoice shows that they were actually paid $25 per hour, and in total $187.50 each for 7 1/2 hours of service. During the recording sessions at Bolic Sound, Tina brought Ike into the studio to hear the highly difficult middle section of "Montana" which had taken the Ikettes a few days to learn and master. Ike listened to the tape and responded "What is this shit?" before leaving the studio. Ike later insisted that Zappa not credit the Ikettes on the released album.

The cover was done by Dave McMacken as somewhat in vein of Salvador Dalí's surreal imagery depicting a two-headed man sitting on a waterbed in a Holiday Inn hotel room surrounded by various objects like a Mothers backstage pass and a television set showing Zappa's face with slime oozing out of it. 

Later reviews evaluated the album far better, with AllMusic writer Steve Huey writing, "Love it or hate it, Over-Nite Sensation was a watershed album for Frank Zappa, the point where his post-'60s aesthetic was truly established". Kelly Fisher Lowe, in The Words and Music of Frank Zappa, wrote that "Over-Nite and Apostrophe (') are important [...] as a return to Mothers of Invention form and as close to traditional pop albums as Zappa would ever come."

The record was certified gold on November 9, 1976.