C Diff ( Clostridioides difficile) can be caused by the use of antibiotics.
C Diff is a pathogenic bacteria that can infiltrate the human gut, causing severe diarrhea, stomach pain, fever, and loss of appetite.
The treatment a physician prescribes is antibiotics. Antibiotics kill beneficial gut bacteria and downstream cause a dysbiosis, an imbalance, of the microbiome.

Spore based probiotics can help to get rid of C Diff symptoms by competing with them for nutrients.
More info here:
https://exclusivelyholistic.com/megaspore-recurrent-c-diff-study/