First published in 2018 There is a long list of symptoms of vitamin B12 deficiency as the vitamin affects several bodily systems. Symptoms of low B12 levels may include poor memory, shortness of breath, depression, yellow skin, a smooth tongue and tingling in your extremities. Vitamin B12 is essential, meaning it must come from food or supplementation. Vitamin B12 is helpful for metabolizing folate, carbohydrates and fat, helps to form red blood cells, produces adrenal hormones and is involved in many other functions.

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